Numerous studies have explored the relationship between selenium levels and overall health, observing an association between adequate selenium intake and support for the body’s natural defenses. While laboratory research has investigated selenium’s role in cellular health, it’s important to approach these findings with the understanding that dietary supplements are intended to support overall well-being and not to diagnose, treat, cure, or prevent any diseases. Selenium is recognized for its contribution to antioxidant processes and supporting the body in maintaining normal function.
Epidemiological studies suggest a connection between antioxidant status and cardiovascular health, highlighting the importance of antioxidants in supporting the body’s defense against oxidative stress. Selenium, recognized for its antioxidant properties, may contribute to the body’s efforts to maintain healthy levels of LDL by supporting antioxidant defense systems. Including selenium as part of a balanced diet is one way to support overall health and well-being.
Selenium and antioxidant activity
The National Academy of Sciences (NAS) published a report on April 11th that explores the evolving understanding of antioxidants and their potential to support overall health. The Council for Responsible Nutrition acknowledges that, although current scientific evidence does not support specific intake recommendations for antioxidants based on disease prevention, there is consensus on a broad range of safe intakes for antioxidant vitamins. This acknowledgment highlights the importance of including antioxidants as part of a balanced diet to support general wellness. It issued higher recommended dietary allowances (RDAs) for vitamins C and E. The new RDAs for antioxidant nutrients are: vitamin C (75 milligrams (mg) for women and 90 mg for men), vitamin E (15 mg), and selenium (55 micrograms (μg))
Research reports note that antioxidant vitamins such as Vitamin C and Vitamin E play important roles in protecting cells from oxidative stress. The review highlighted that Vitamin E helps inhibit LDL oxidation—an important factor in maintaining overall cardiovascular health—and may support arterial wellness through additional mechanisms. It also stated that Vitamin C helps reduce oxidative damage, including in eye tissues, suggesting a potential role in supporting long-term eye health and clarity.
The NAS report also established tolerable upper intake levels (ULs) for vitamin C (2,000 mg), vitamin E (1,000 mg) and selenium (400 μg). ULs for adults are set to protect the most sensitive individuals of the general population
Selenium and healthy blood sugar levels
Selenium has been studied for its ability to mimic certain insulin-like actions at the cellular level. Laboratory research shows that selenium can influence glucose uptake and support key metabolic pathways, including glycolysis, gluconeogenesis, fatty acid metabolism, and the pentose phosphate pathway. Emerging evidence also suggests that selenium may play a role in normal insulin-signaling processes by helping activate proteins involved in metabolic regulation. In addition, selenium is well recognized for its antioxidant properties, which help the body manage oxidative stress, a factor that can affect overall well-being. Through these combined functions, selenium helps support metabolic health and contributes to the maintenance of healthy nerves, eyes, and other systems by reinforcing the body’s natural defense mechanisms against oxidative stress.
Studies have observed an association between selenium levels and joint health, suggesting that adequate selenium intake may support joint comfort and mobility. Selenium’s antioxidant properties, recognized for their potential to protect against oxidative stress, may contribute to the overall maintenance of healthy joints. While research is ongoing, incorporating selenium as part of a balanced diet emphasizes its role in supporting the body’s natural defenses and promoting general well-being
Selenium Support in Overall Health and Immune Function
Nutritional support is an important consideration in the overall care of individuals with chronic health conditions. A study observed 24 children with HIV over a five-year period, noting an association between selenium levels and overall health outcomes. This research underscores the significance of monitoring nutritional status as part of comprehensive health management. Ensuring adequate selenium intake, as part of a balanced diet, may play a role in supporting the body’s general well-being and resilience
Selenium and Central Nervous System Support
Research indicates that maintaining adequate selenium levels may play a role in supporting cognitive health and overall well-being. Observational studies have explored selenium’s potential to support mood, mental clarity, and feelings of energy, with some findings suggesting a link between selenium status and these aspects of wellness. While early evidence is encouraging, additional research is needed to fully clarify selenium’s role in cognitive support. Including selenium as part of a balanced diet helps ensure sufficient intake of this essential nutrient, which contributes to the body’s natural processes and overall health.
