Selenium Deficiency and Associated Health Concerns

Research suggests that inadequate selenium intake may reduce the activity of selenium-dependent antioxidant enzymes, which play an important role in the body’s natural defense mechanisms. Reduced activity of these enzymes has been associated with various functional disturbances, highlighting the importance of maintaining sufficient selenium levels as part of overall health.
Very low selenium status has been associated with certain health conditions observed in regions with selenium-deficient soil, including a specific form of juvenile cardiomyopathy (Keshan’s Disease) and a type of chondrodystrophy (Kaschin–Beck Disease). These associations highlight the importance of adequate selenium intake for supporting overall health.

Selenium plays an important role in supporting the body’s immune defenses, particularly through its involvement in antioxidant enzymes that help manage oxidative stress. Adequate selenium intake has been associated with healthy immune cell activity, contributing to the body’s natural resilience and ability to respond to everyday wellness challenges. Research suggests that selenium helps maintain normal immune function by supporting antioxidant pathways and aiding the body’s natural processes that protect cells from oxidative damage. While ongoing studies continue to explore the full extent of selenium’s role in immune health, maintaining sufficient selenium levels through diet or supplementation can be an important part of supporting overall well-being.

Adequate selenium intake is essential for maintaining healthy thyroid function, as selenium-dependent enzymes play a key role in the conversion of thyroid hormones and the protection of thyroid tissue from oxidative stress. Low selenium status may compromise these processes, potentially affecting normal hormone metabolism and overall thyroid health. Ensuring sufficient selenium levels as part of a balanced diet helps support the body’s natural thyroid function and contributes to overall metabolic well-being.